Michele Jen, M.S.
Ph.D. Student, Biomedical Engineering
Contact: m-jen at northwestern.edu
Research interests: Substrate-mediated gene delivery for vascular tissue engineering
Direct protein delivery from scaffolds generally poses several challenges such as limited protein loading capacity onto scaffolds, decreased effectiveness of the protein for extended periods, and altered protein function due to immobilization techniques onto scaffolds. For these reasons, much attention has been paid to gene delivery as an alternative approach by allowing the transfected seeded or infiltrating cells to express the desired protein for prolonged periods. The goal of this project is to use poly(1,8 octanedio-co-citrate) as a substrate-mediated gene delivery system for vascular tissue engineering.Selected Awards / Honors: